Several numerical methods of differential equations and their applications in ballistic calculation are discussed for the purpose of simplification of the dynamic differential equations of projectile trajectory.Program simulations of Euler method,Heun method,lassic fourth-order Runge Kutta(RK4)method,ABM method and Hamming method are achieved based on Matlab.In addtion,the approximate solutions,local truncation errors and calculation time of the dynamic differential equations are obtained.By analyzing the simultaion results,the advantages and disadvantages of these methods are compared,which provides a basis for choice of ballistic calculation methods.