B族链球菌(group B Streptococcus, GBS)是一种导致新生儿败血症和脑膜炎的重要致病菌。在世界范围内,GBS在孕妇体内广泛定植,可定植在孕妇的正常胃肠道和泌尿生殖系统中,并在某些条件下转变为感染状态,给围产期妇女及新生儿的健康产生巨大影响。所以早期诊断GBS感染,并在及时给予适当的干预,可降低新生儿的感染率。本文就妊娠期B族链球菌感染的发病机制、感染高危因素及患者的筛查和防治方面的研究进展进行阐述。Group B Streptococcus (GBS) is one of the important pathogenic bacteria which can cause neonatal sepsis and meningitis. Worldwide, Group B Streptococcus (GBS) is widely colonized in pregnant women, commonly residing in the normal gastrointestinal tract and the urogenital system. Under certain conditions, it can transition from colonization to an infectious state, posing significant health risks to both perinatal women and newborns. Therefore, early diagnosis of GBS infection and giving appropriate intervention in time can reduce the infection rate of newborns. This paper describes the pathogenesis of group B streptococcal infection, high-risk factors for infection, and strategies for screening and prevention and treatment of patients.
