Based on the research on corrosion-resistance of titanium in various media and a great deal of tests, a newchemical cleaning process for titanium-made equipment was developed and applied to titanium-made heat exchangersof a homemade multi-stage flash distiller for sea-water desalination in Tianjin Dagang Power Plant. Scale in the tubeswas removed completely as inspected by the experts. Testing results of hydrogen content and metallographic structureof titanium tubes showed that the cleaning was successful without any damages to the equipment.[