[Objective] The research aimed to establish a optimized combination of intercropping and fertilization application technology of intercropping sesame （Sesamum indicum） and peanut（Arachis hypogaea）. [Method] Double factor randomized block design （2 fertilization methods and 5 ratios） was adopted, with 10 treatments, 3 repeats. There were a total of 30 plots, with plot area of 12.0 m2. Two fertilization methods included C1 [base fertilizer （540 g/plot compound fertilizer ＋ topdressing （90 g urea）] and C2 [all as base fertilizer （540 g/plot compound fertilizer）]. Five different proportions （sesame： peanut） were M1（2∶4）, M2（2∶6）, M3（1∶4）, monoculture sesame （CK1） and monoculture peanut （CK2）, respectively. [Result] Output value and land equivalent ratio （LER） of C1M2 treatment （6 lines peanut/2 lines sesame, base fertilizer 540 g/plot （compound fertilizer） ＋ （topdressing urea 90 g） were the highest of 22 378.68 yuan/hm2 and 1.56 respectively; sesame yield was 641.64 kg/hm2 and peanut yield was 2 506.67 kg/hm2. Output-input ratio was 4.94. The income was increased by 32.32% and 95.97% compared with only planting of peanuts and sesame. [Conclusion] The study provided a theoretical basis for finding the best intercropping combinations of sesame and peanut and rational application fertilizations.
