随着近些年中国经济迅猛发展,国际地位的不断攀升以及医学高等教育的国际化,来华求学的留学生人数逐年增多。如何提高留学生的教学质量是当前每个医学院校的首要任务。扎实的人体寄生虫学知识是完善留学生医学知识体系、通过美国执业医师考试USMLE (United States Medical Licensing Examination)不可或缺的条件。为了准确、客观地评价留学生的人体寄生虫课程学习效果,石河子大学医学院病原免疫教研室构建了留学生人体寄生虫考试试题库。试题库不仅是检验留学生学习效果的重要手段,也是实现教考分离的举措之一;试题库极大地提升了阅卷效率并能有效地减少误判率。构建留学生试题库是医学教育考试、管理从传统向现代化、科学化、规范化过渡的必经之路。本文从试题建设的导向、和临床结合的状况、题型的设置和比例、题目的数量、分值的设置、题型难易比例、答题时间等介绍本教研室留学生人体寄生虫试题库建设的体会,以期为留学生适应、通过USMLE考试提供帮助。With the rapid development of China’s economy in recent years, the continuous rise of China’s international status and the internationalization of medical higher education, the number of international students studying in China is increasing year by year. How to improve the teaching quality of international students is the primary task of every medical college. Solid knowledge of human parasitology is an indispensable condition for international students to improve their medical knowledge system and pass the United States Medical Licensing Examination (USMLE). In order to accurately and objectively evaluate the learning effect of the human parasite course for international students, the Department of Pathogen and Immunity of the School of Medicine of Shihezi University established the test bank of human parasite examination for international students. The test bank is not
目的:应用多位点数目可变串联重复序列分析(multiple loci VNTR analysis,MLVA)技术,对新疆喀什地区维吾尔族结核病患者结核分枝杆菌临床分离株进行基因分型,探讨5个数目可变串联重复序列(VNTR)基因型种类及其分布。方法:收集结核分枝杆菌,采用PCR和琼脂糖凝胶电泳技术,结合BioNumerics5.0软件,对其5个VNTR位点进行结果分析。结果:分离出58株结核分枝杆菌,分为4个基因群21个基因型,分别为Ⅰ群占19.1%,含7个基因型;Ⅱ群占3.4%,含2个基因型;Ⅲ群占67.2%,含9个基因型;Ⅳ群占10.3%,含5个基因型。结论:新疆喀什地区维吾尔族结核病患者的结核分枝杆菌存在明显的基因多态性,且存在主要流行菌群。