Based on K ε two equation turbulence model,the air distribution and contamination field under different conditions was numerically simulated in a vector flow cleanroom.Special mesh system was introduced to deal with the quarter circle shaped inlets.Model experiments were also made.By analysis of numerical as well as experimental results,we made some predictions about flow characteristics,contaminant control effect and ventilation performance of this energy saving cleanroom.It has been proved that the vector flow can meet class 100 of Fed. St.with 13 to 12 conventional air change per hour,and reduce layer height and simplify air clean system.