The effect of heat treatment on the transformation temperature of Ti?52.2%Ni (mole fraction) alloy was studied using differential scanning calorimetry (DSC). The transformation temperatures of the alloy can be adjusted effectively by heat treatment. Dense and stable SiO2 coatings were deposited on the surface of the pre-oxidized TiNi alloy by sol?gel method. The bonding strength of films and matrix was (65.9±1.5) N. The electrochemical corrosion test shows that the TiNi alloy with SiO2 coating has excellent corrosion resistance in the Hank’s simulated body fluid. The release behaviors of Ni ion of the alloy with and without SiO2 coating implanted in the acoustic vesicle of guinea pig were studied by EDS testing, which was inhibited effectively by the dense and stable SiO2 coating on the alloy.