Objective: To study the relationship between menstrual cycle and characteristics of clinical seizures and EEG in woman patients with epilepsy.Method:Clinical analysis was done in one hundred and twenty woman patients with epilepsy.Results:Thirty-eight percent of patients was related to the menstrual cycle, and 68.9%.of them was menstrual epilepsy. In patients with epilepsy related to the menstrual cycle, most of them showed disorders in development ,memory and local nerve function, and epileptic seizures more than two times in a week. A significant difference was noted as compared with the control group(P<0.05).EEGs mainly showed background abnormality and local slow waves(P<0.01).Conclusions:A relationship was noted between the menstrual cycle and woman epileptic seizures. It might be of important clinical significance in guidance of studing the inducing cause and treatment of woman epileptic patient.[