Objective:To evaluate the risk of malignancy indices(RMI-1 and RMI-2) based on serum CA125,menopausal status,and ultrasound score for forecast the patients with ovarian tumors.Methods:The sensitivity,Specificity,positive predictive value of serum CA125,ultrasound scores and menopausal status,separately and combined into the RMI-1 andRMI-2,for differential diagnosis of ovarian tumors.Results:Benign ovarian tumors 76 cases and ovarian cancers 37 cases were randomly measured.The RMI-1 at a cut off value of 100 gave a sensitivity of 81.1%,specificity of 93.4%.A sensitivity of 78.3%,specificity of 96.0% were given at a cut off value of 125.RMI-2 gave a sensitivity of 81.0%,specificity of 89.5% and 78.3%,90.8% respectively.For all cut off values between 50 and 200,RMI-1 performerd better than that of RMI-2.RIM was more accurate than menopausal status,ultrasound score,and serum CA125 separately in diagnosing ovarian tumors,and was comparable with other scoring systems.Conclusions:RMI-1 is more reliable in discrimination benign and malignant ovarian tumors than that of RMI-2.RMI is a simple,practical and reliable method which can be used in gynecologic clinics.
