35 cases (rnale 24, fema1e 11, 38 eyes)of retinoblastoma (RB) were analysed clini-cally in this Paper. The ages of the patientsrangec1 from 50 days to lO years (<5 yearsold colistittlted 91. 43% of all the patients )The cotlrse of disease was shouter than tenmoilths in 3O cases. 24 cases had been 0per-ated on. (ophthalmectomy to 2O eyes, exen-teration of the orbital contents t0 4 eyes ).we found that the invading rate of opticnerves was mtlch higher in glaucoma andextraocular period than that in intraocularperi0d by analysing the results of B Alultra-sonic scan and patholgic examination. 5caese were followed up. One case Survivedafter 13 years and an0ther one recurred intwo monthe.