To study the distribution characteristics of Hepatitis B virus (HBV) genotypes in groups of the Zhuang nationality of Baishe in Guangxi, the PCR sandwich hybridization-ELISA technique was used to determine the genotypes in 30 patinets of Zhuang nationality with hepatitis B. Geontype B, C, D and non A^F were found in this group, in which 56.6% of them were type D,46.6% type C,33.3% typeA^F, 20% type B, Most patients were found with types C+D, D+B or C+B. It is suggested that there are genotypes D, C, B and non A^F in this area, and the major one was genotype D. There are mixture of genotypes C+D, B+C, D+B in this region, so the HBV genotype might be associated with area and nationality.
