To introduce the advances of experimental research on acupuncture and moxibustion for treatment of Women's Climacteric Syndrome.The recent years experimental research literature of acupuncture and moxibustion for treatment of Women's Climacteric Syndrome were reviewed.The research literatures on acupuncture treatment were major,focusing on the field of acupuncture and moxibustion regulating hypothalamic-pituitary-gonad axis and nerval-endocritic-immune net.Acupuncture and moxibustion could regulate the endocrine environment of menopausal women.Taking advantage of combination biomedicine with multi-sciences,to improve the acupuncture and moxibustion curative effct and probe the mechanism of menopausal pathology and acupuncture and moxibustion function to Women's Climacteric Syndrome,is the research direction afterward.