The objective of this study is to investigate the hemodynamics in patient-specific thoracic aortic aneurysm and discuss the reason for formation of aortic plaque.A 3-Dimensional pulsatile blood flow in thoracic aorta with a fusiform aneurysm and 3 main branched vessels was studied numerically with the average Reynolds number of 1399 and the Womersley number of 19.2.Based on the clinical 2-Dimensional CT slice data,the patient-specific geometry model was constructed using medical image process software.Unsteady,incompressible,3-Dimensional Navier-Stokes equations were employed to solve the flow field.The temporal distributions of hemodynamic variables during the cardiac cycle such as streamlines,wall shear stresses in the arteries and aneurysm were analyzed. Growth and rupture mechanisms of thoracic aortic aneurysm in the patient can be analyzed based on patient-specific model and hemodynamics simulation.
Ai-Ke Qiao,~(1,a)) Wen-Yu Fu,~(2,3) and You-Jun Liu~(1,b)) 1)College of Life Science and Bioengineering,Beijing University of Technology,Beijing 100124,China 2)College of Mechanical and Electrical Engineering,Beijing Union University,Beijing 100124,China 3)College of Mechanical Engineering and Applied Electronics Technology,Beijing University of Technology, Beijing 100101,China
目的法洛四联症(tetralogy of Fallot,TOF)是出现在新生儿中一种常见的先天性心脏病,其初期治疗的关键是在主动脉和肺动脉之间建立人工侧支循环,本研究从血流动力学角度探讨升主动脉与右肺动脉吻合的手术方案对TOF治疗的有效性。方法采用计算流体力学的方法对TOF手术模型进行数值模拟,重点考察搭桥管径对手术效果的影响,并根据增流率、分流率、能量损失、压力分布、壁面切应力分布等血流动力学参数对手术方案进行评价。结果实施搭桥手术后,左、右肺动脉出口的血流量有不同程度的增加。结论升主动脉与右肺动脉吻合的搭桥方案,可以在一定程度上缓解肺动脉狭窄造成的血流供给不足。
