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国家自然科学基金(81360567)

作品数:7 被引量:48H指数:3
相关作者:许建峰武永利林瑞珠王英絮牛子瞻更多>>
相关机构:宁夏医科大学教育部更多>>
发文基金:国家自然科学基金宁夏回族自治区自然科学基金更多>>
相关领域:医药卫生更多>>

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刺络放血的临床应用体会被引量:3
2014年
温阳化瘀强调了通过药物或者艾灸的温阳通经作用可使瘀血消散,阳气充足可以鼓邪外出,使得体表出现瘀络,通过刺络放血可以祛除瘀血。瘀祛神调说明了瘀血被祛除,新血生而供养和调节心神,从而达到调节全身脏腑经络目的。瘀消正复阐释了放血后皮下瘀血或瘀斑消散过程中激发机体正气之理。
许建峰林瑞珠武永利王英絮张跃全牛子瞻席朝垒
关键词:瘀血灸法刺络放血
回医烙灸疗法配合护理干预对类风湿性关节炎患者疼痛及血清IL-2、TNF-α水平影响的研究被引量:21
2014年
目的 探讨回医特色烙灸疗法配合护理干预对类风湿性关节炎(RA)患者疼痛及治疗前后血清IL-2和TNF-α的影响.方法 选取宁夏医科大学总医院中医骨伤科201 1年5月至2013年9月RA住院患者89例,随机分为对照组43例与治疗组46例.2组患者取穴均采用整体与局部相结合的方法,其中对照组由医生采用温针疗法,30 min/次,1次、d,常规护理;治疗组由专职中医护士采用回医铁质灸具,直接灸腧穴部位,以局部皮肤微微发红为度,30 min/次,1次、d,并在常规护理基础上,重点结合说理开导、情感相胜、暗示转移、定志安神等中医心理护理指导.均10次为1个疗程,疗程间休息3~5 d,3个疗程后进行疗效评价.同时,应用数字疼痛评分法等级量表(NPRS)评估2组患者治疗前后疼痛程度;采用心理健康测试量表(症状自评量表SCL-90)评定2组患者治疗前后心理情绪状况,应用放免法测定2组患者治疗前后血清IL-2和TNF-α含量.结果 治疗组总有效率为89.13%,对照组为74.42%,2组间比较,差异有统计学意义;2组治疗后NPRS、SCL-90评分较治疗前均有明显改善,差异有统计学意义;2组治疗后NPRS、SCL-90评分比较治疗组优于对照组,差异有统计学意义.2组治疗后血清IL-2和TNF-α水平较治疗前均有明显改善,差异有统计学意义;2组治疗后IL-2和TNF-α水平比较治疗组优于对照组,差异有统计学意义.结论 回医烙灸疗法配合中医心理护理干预措施可以有效改善RA患者的疼痛状况,缓解心理焦虑,提高血清IL-2、TNF-α水平,提升患者生活质量,促进病症康复.
魏雪红鲁亚玲段梅欣武永利许建峰
关键词:类风湿性关节炎护理干预INTERLEUKIN-2
回医烙灸对大鼠腰椎间盘退变模型软骨基质的影响被引量:2
2018年
目的:观察回医烙灸疗法对大鼠腰椎间盘退变模型软骨细胞外基质的影响。方法:将SD大鼠40只,随机分为正常对照组、假手术组、模型对照组和回医烙灸组,每组10只。采用针刺间盘方法制备大鼠腰椎间盘退变模型。回医烙灸组在造模4 w后,在腰椎局部行回医烙灸疗法,每周2次,每次20 min,干预6 w。正常对照组、假手术组和模型组不予干预。4组动物干预8 w后处死取材,采用分光光度法检测椎间盘蛋白多糖,II型胶原纤维、MMP-3、TIMP-1蛋白的表达采用免疫组化方法进行检测。结果:回医烙灸组蛋白多糖和II型胶原纤维阳性细胞数明显高于模型对照组(P<0.05)。回医烙灸组间盘软骨组织MMP-3的阳性细胞数低于模型对照组(P<0.05),软骨组织TIMP-1的阳性细胞数高于模型对照组(P<0.05)。结论:回医烙灸疗法可以减少大鼠腰椎间盘退变模型软骨组织基质的降解,并可以调节软骨基质降解相关因子的表达,从而延缓腰椎间盘的退变。
尤娜许建峰许建峰林瑞珠林瑞珠林瑞珠马玉宝牛子瞻
关键词:腰椎间盘退变软骨细胞基质
胃护理干预联合回医烙灸治疗老年原发性骨质疏松症(骨蚀)随机平行对照研究被引量:2
2019年
[目的]观察脾胃护理干预联合回医烙灸治疗老年原发性骨质疏松症(骨蚀)疗效。[方法]使用随机平行对照方法,将85例住院及门诊患者按就诊顺序号抽签随机分两组。对照组41例温针灸(直径0.30mm、长25~40mm毫针),脾胃经整体取穴:三阴交、血海、足三里、梁门、中脘、内关、阴陵泉、脾俞、胃俞;随证局部取穴,血海、梁门泻法为主,三阴交、足三里、中脘、内关、阴陵泉、脾俞、胃俞,留针30min,留针期间加灸,每5min行针1次,1次/d;常规护理:①心理护理:据文化层次,年龄、爱好、生活习惯等针对性心理疏导;②健康教育:了解OP的预防,发病机制和康复等问;③饮食护理:增加钙、含维生素D多食物;④运动指导:依年龄、性别、健康状况、体能等选择适当的方式、时间、强度等;⑤用药护理:根据疏松程度,按医嘱及时、正规用药。干预组44例脾胃护理:养神,疏导患者思维、精神,与患者谈心、提供阅览相关书籍等,告诫少思寡欲;省言,"服药讫,忌语话一二时辰许";调情志,情绪疏导,有的放矢做好心理护理,观其表,调其神,说理开导、定志安神、暗示转移;节饮食,辨证膳食指导,遵循饮食权衡之法,合理选用寒温适宜,避免饮食偏嗜;服药后忌酒、湿面、大料物之类,宜温食及薄滋味;慎起居,忌劳倦,告诫患者忌浴当风、汗当风,调适生活起居;正常劳动和体育锻炼,避免劳累;常规护理同对照组;回医烙灸:烙灸器烧红,灸,以局部皮肤微微发红为度,皮肤溃破、流水、流脓,注意局部清洁,预防感染,30min/次,1/d。连续干预治疗10d为1个疗程,疗程间休息3~5d,继续下一疗程。观测临床表现、NPRS评分、SF-36评分、不良反应。连续干预治疗6疗程(60d),判定疗效。[结果]临床疗效、骨密度疗效治疗组优于对照组(P<0.05)。NPRS评分两组均有明显降低(P<0.05),治疗组降低优于对照组(P<0.01)。SF-36评分两组均有�
魏雪红鲁亚玲段梅欣武永利许建峰李卫强
关键词:老年原发性骨质疏松症骨痿骨痹骨蚀随机平行对照研究
Acupuncture-movement therapy for acute lumbar sprain: a randomized controlled clinical trial被引量:15
2016年
OBJECTIVE: Several studies have reported that acupuncture is effective for treatment of acute lumbar sprain, but they neglected to consider that acupuncture cannot remarkably improve lumbar activity. We performed a randomized controlled trial to evaluate the effect of acupuncture-movement therapy versus conventional acupuncture in the trea ment of acute lumbar sprain. METHODS: Sixty patients were randomized into four groups: the acupuncture-movement (AM) group, sham acupuncture-movement (SAM) group, conventional acupuncture (CA) group, and physical therapy (PT) group. Patients in the AM group were treated with acupuncture at Yintang (EX-HN 3) and exercise of the lumbar region during acupuncture. Patients in the SAM group were treated with sham acupuncture at Yintang (EX-HN 3) and exercise of the lumbar region during sham acupuncture. Con- ventional acupuncture was performed in the CA group, and physical therapy was applied in the PT group. Each treatment lasted for 20 min. Patients were assessed before and after treatment using a visual analogue scale (VAS) and the Roland Morris Questionnaire (RMQ). RESULTS: The VAS and RMQ scores in the AM group were significantly lower after than before treatment (P 〈 0.01). The AM group reported lower RMQ scores in after-treatment and 24 h after treatment and lower VAS score in 24 h after treatment in comparison with those of the CA, SAM, and PT groups (P 〈 0.05). CONCULSlON: Acupuncture-movement therapy is effective for treating acute lumbar sprain with a persistent pain-relief and remarkable improvement of lumbar activity. Movement, that is, lumbar exercise during acupuncture, enhances the effect of acupuncture.
Lin RuizhuZhu NingLiu JianLi XinjianWang YueZhang JieXi Chaolei
关键词:ACUPUNCTUREMOVEMENTEXERCISE
Chronic fatigue syndrome treated by the traditional Chinese proce-dure abdominal tuina:a randomized controlled clinical trial被引量:3
2017年
OBJECTIVE: To evaluate the effect of the traditional Chinese procedure abdominal Tuina(AT) on chronic fatigue syndrome(CFS).METHODS: This randomized, single assessor-blinded clinical trial was carried out from May 2014 to April 2015. Eighty participants in the trial were divided randomly into two groups: experimental group and control. The experimental group(40 cases) was treated by AT and the control group(40 cases) by acupuncture. Each treatment was conducted once a day, 5 d for one course, at an interval of 2 d between each course. The whole treatment course lasted for 4 weeks. To ascertain the effect of AT and acupuncture, Fatigue Scale-14(FS-14), Self-rating Anxiety Scale(SAS) and Hamilton Rating Scale for Depression(HAMD) scores were used before and after treatment. Patients were followed up for3 months after treatment.RESULTS: After treatment for 4 weeks, 77 patients(39 cases in the experimental group and 38 cases in the control group) completed the trial. The FS-14,SAS and HAMD scores decreased(P < 0.05) significantly compared with those before treatment in both groups. The FS-14 and HAMD(P < 0.05) scores in the experimental group were much lower than those in the control group. The difference in SAS scores between the two groups was not significant.In the final follow-up, CFS in two cases in the experimental group and three in the control group recurred, but the difference was not significant. The scores for the FS-14, SAS and HAMD in the experimental group were superior to those of the control group, and the difference was significant(P < 0.05).No serious adverse events and few adverse events were observed.CONCLUSION: AT elicited a more efficacious effect than acupuncture alone on CFS.
Li HuananWang JinguiZhang WeiZhao NaHai XinhuaSun ShiquanSun QingHan YihaoZhang RunchenMa Fei
关键词:RANDOMIZEDSELF-RATINGANXIETYHAMILTON
回医烙灸疗法对大鼠腰椎间盘退变模型软骨细胞凋亡的影响被引量:3
2017年
目的 :观察回医烙灸疗法对大鼠腰椎间盘退变模型软骨细胞凋亡及相关凋亡因子的影响。方法 :将SD大鼠40只,随机分为正常对照组、假手术组、模型对照组和回医烙灸组,每组各10只。采用针刺间盘方法制备大鼠腰椎间盘退变模型。回医烙灸组在造模4周后,在腰椎局部行回医烙灸疗法,每周2次,每次20 min,干预6周。正常对照组、假手术组和模型组不予干预。4组动物干预8周后处死取材,软骨细胞凋亡用TUNEL法检测,Bcl-2、Bax、Caspase-3蛋白的表达采用免疫组化方法进行检测。结果 :回医烙灸组凋亡指数明显低于模型对照组(P<0.05);回医烙灸组和正常对照组、假手术组比较,差异无明显统计学意义(P>0.05)。回医烙灸组间盘软骨组织Bax和Caspase-3的阳性细胞平均数低于模型组(P<0.05),软骨组织Bcl-2的阳性细胞平均数高于模型对照组(P<0.05)。结论 :回医烙灸疗法可以减少大鼠腰椎间盘退变模型软骨细胞的凋亡,并可以调节软骨细胞凋亡相关因子的表达,从而延缓腰椎间盘的退变。
许建峰许建峰林瑞珠林瑞珠林瑞珠武永利
关键词:腰椎间盘退变软骨细胞凋亡
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