Acting as an important driving force for the change of the regional land use,the change of industrial structure also has some influences on the ecological environment.The assessment and mechanism analysis of these influences will be beneficial to the sustainable development of regional economy and the im- provement of relationships between man and earth.Taking Chuzhou City in Anhui Province as an example,on the basis of a qualitative analysis of the influence of the development of differ- ent industry on the regional ecological environment,this paper builds the influence factor of industrial structure on natural envi- ronment and the influence index of industrial structure on natural environment,makes a quantitative assessment of the change of the industrial structure and its comprehensive influences on the eco- logical environment in the Chuzhou City from 1974 to 1995. Studies show that,during the analysed period,Chuzhou City's industrial structure has changed markedly,having undergone two transformations.The influence of industrial structure on natural environment from 1974 to 1995 increased as a whole,while from 1996 to 2004,the influence of industrial structure on natural en- vironment decreased year-on-year.These changes indicate that the regional change of industrial structure results in better ecological effects.Finally,we propose appropriate regulatory measures ac- cording to our research results.