＜正＞Sulfoximines（sometimes also called sulfoximides）are structurally unique derivatives of sulfones,which are a...
Jinbo Hu,Wei Zhang,Xiao Shen and Tao Luo Key Laboratory of Organofluorine Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,345 Ling-Ling Road,Shanghai 200032,China
Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides has been successfully achieved.It was found that both the catalytic amount of sodium dithionite (Na2S2O4) and the stoichiometric amount of triethylborane (Et3B)/air can efficiently initiate the current free-radical atom transfer reaction.
ZHU JieMing,WANG Fei & HU JinBo CAS Key Laboratory of Organofluorine Chemistry
Difluoromethyltri（n-butyl）ammonium chloride 1 was found to be an effective difluorocarbene reagent for O-, S-, N-, C-difluoromethylation under basic conditions. It is particularly remarkable that, when only 1.2 equivalent of reagent 1 was used, the difluoromethylated products were obtained in moderate to excellent yields.
