[ Objective ] The paper was to explore the combined application technique of organic fertilizer and two biocontrol agents against pepper blight in green- house hot pepper in Qinghai Province. [Method] By L4 (23)orthogonal design, the effects of combined application of two biocontrol agents against pepper blight and organic fertilizer on control effects against pepper blight and the yield of hot pepper were studied in greenhouse hot pepper base in Ledu County of Qinghai Province. [ Result] The effects of various factors affecting the relative control effect against pepper blight in sequence were biecontrol agent A5 〉 biecontrol agent B2 〉 organic fertilizer, and the optimal combination was organic fertilizer 1 800 kg/hm^2, agent B2 30 kg/hm^2 and agent A5 45 kg/hm^2. The effects on hot pepper yield in sequence were organic fertilizer 〉 biocontrol agent B2 〉 biocontrol agent AS, and the optimal combination was organic fertilizer 900 kg/hm^2 , agent 132 15 kg/hm^2, agent A5 22.5 kg/hm2. [ Conclusion] Combined with control effect of pepper blight and yield benefit, the application technique of biocontrol agents pro- moted in local hot pepper production could be confirmed as follows : agent A5 45 kg/hm^2, agent B2 15 kg/hm^2, organic fertilizer 900 kg/hm^2 ; the field control effect at this moment could reach 76.31%, the yield could reach 35 573 kg/hm^2 , and the newly increased output value could be 13 029 yuan/hm^2 with input and output ratio of 1: 7.9.