Considering the uncertainty of material performance, geometric characteristic and analysis method, the analysis of statistical parameters of the resistance of cast ball-and-socket support joints and the reliability analysis are carried out by JC method (improved first-order second-moment method) based on the relevant experimental data. Results show that the resistance partial factor of the joint increases with the increase of the reliability index. The resis- tance partial factors are suggested corresponding to the reliability index under different load combinations. Moreover, the suggested resistance partial factor is adopted in reliability design, and it is found that the reliability index of the joint is larger than the target reliability index. The optimal load combination is the one in which live load plays an im- portant control role. Finally, based on the suggested resistance partial factors, the reliability analysis of cast bail-and- socket support ioints of a proiect is conducted.