In order to cultivate the top-notch innovative talents with the intemational perspectives, on the basis of the principles of objective, utility, humanities and practice, medical institutions should update the concept of talent cultivation led by employment, innovate teaching mode by deepening teaching reform, optimize the teaching staff by strengthening cooperation between college and enterprise, widen the practical teaching by participating interaction with pharmaceutical industries, and improve the teaching supervision system by implementing quality requirements to construct quality security system in the cultivation of top-notch innovative medical talents.