Air pollution is a significant risk factor contributing to the burden of disease in China.Health risk assessment and management are important to reduce the impact of air pollution on public health.To help formulate standardized health risk assessment techniques,a series of studies were conducted from 2006 to 2019.Through systematic review,study of molecular mechanisms,epidemiological investigation,and health effect monitoring,the overall project established a monitoring and evaluation indicator system,a comprehensive information platform,software for automatic data cleaning,and standardized health risk assessment techniques.Technical specifications have been issued by the National Health Commission for promoting health risk assessments across China.This paper introduces the project,the research approach,its main research accomplishments,innovations,and public health significance,and describes directions for further research.