New layered perovskite compounds, AgxNa2-xLa2Ti3O10 (x=0.2, 0.3 and 0.5) were synthesized by an ion-exchange reaction of Na2La2Ti3O10 with AgNO3 solution and characterized by energy dispersive X-ray analysis(EDX), X-ray diffractometry(XRD), scanning electron microscopy(SEM) and X-ray photoelectron spectroscopy(XPS). The ion-exchange processes were optimized, and the antibacterial activity, light permanency and water-resistance were evaluated. Surprisedly, no significant changes in crystal structure of Na2La2Ti3O10 are found by the exchange of silver ions. The Ag0.3Na1.7La2Ti3O10 particles conglomerate obviously with irregular shape and size. Ag0.3Na1.7La2Ti3O10, possessing the minimum inhibitory concentrations(MICs) against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus) of 180 mg/L and 240 mg/L, has high antibacterial activity, good light permanency and water-resistance. The ionic state silver in AgxNa2-xLa2Ti3O10 is the antibacterial active component.
