Three cyclohexyltin complexes of N-（3,5-dibromosalicylidene）valine（H_2L）, Cy_3Sn（HL）（1）, Cy_2SnL（2）, and Cy2 SnL ·Cy_3Sn Cl（3）（Cy = cyclohexyl）, have been synthesized and characterized by elemental analysis, IR, and ~1H and ^（13） C NMR spectra. The crystal structures of 2 and 3 have been determined. Complex 2 belongs to the monoclinic system, space group P21/n with a = 21.250（8）, b = 10.837（4）, c = 23.050（8） ？, b = 93.193（9）°, V = 5300（3） ？~3, Z = 8, D_c = 1.659 g/cm^3, m = 4.004 mm^（-1）, F（000） = 2624, R = 0.0471 and wR = 0.1015. Complex 3 belongs to the monoclinic system, space group P21 with a = 10.3452（10）, b = 18.7665（18）, c = 12.1483（12） ？, b = 103.374（2）°, V = 2294.5（4） ？3, Z = 2, D_c = 1.542 g/cm^3, m = 2.923 mm^（-1）, F（000） = 1072, R = 0.0428 and wR = 0.0936. Complex 2 has a distorted trigonal bipyramidal geometry with the axial locations occupied by one carboxylate oxygen and a phenolic oxygen of the ligand, and 3 reveals that the two tin atoms are joined via the carbonyl atom of the ligand to form a mixed organotin binuclear complex. Bioassay results show that 1 and 2 have good in vitro antibacterial activity against Escherichia coli.
An efficient approach to sulfur-bridged imidazopyridines has been developed under metal-free conditions using inexpensive sulfur powder as the sulfur source.Most appealingly,the reaction can proceed smoothly without addition of any additives,ultimately decreasing the production of chemical waste.The inexpensive and green method should provide a useful strategy for constructing a library of novel and biological interesting heteroaromatic sulfides.
Ziyu GanXiaolong ZhuQiuli YanXiuyan SongDaoshan Yang
An efficient and eco-friendly protocol for the construction of naphtho[2,1-d]thiazol-2-amines through visible-light photoredox-catalyzed C(sp2)–H/S–H cross-dehydrogenative coupling reactions between 2-isothiocyanatonaphthalenes and amines was established.In this reaction,the new C–N and C–S bonds are formed simultaneously in a single step.This new method provides a straightforward approach for constructing valuable sulfur-containing compounds.
Ziyu GanGuoqing LiXiaobo YangQiuli YanGuiyun XuGaoyang LiYuan-Ye JiangDaoshan Yang
