Receiver operating characteristic (ROC) curves are often used to study the two sample problem in medical studies. However, most data in medical studies are censored. Usually a natural estimator is based on the Kaplan-Meier estimator. In this paper we propose a smoothed estimator based on kernel techniques for the ROC curve with censored data. The large sample properties of the smoothed estimator are established. Moreover, deficiency is considered in order to compare the proposed smoothed estimator of the ROC curve with the empirical one based on Kaplan-Meier estimator. It is shown that the smoothed estimator outperforms the direct empirical estimator based on the Kaplan-Meier estimator under the criterion of deficiency. A simulation study is also conducted and a real data is analyzed.
This paper considers the monotonic transformation model with an unspecified transformation function and an unknown error function, and gives its monotone rank estimation with length-biased and rightcensored data. The estimator is shown to be√n-consistent and asymptotically normal. Numerical simulation studies reveal good finite sample performance and the estimator is illustrated with the Oscar data set. The variance can be estimated by a resampling method via perturbing the U-statistics objective function repeatedly.
This paper proposes a unified semiparametric method for the additive risk model under general biased sampling. By using the estimating equation approach, we propose both estimators of the regression parameters and nonparametric function. An advantage is that our approach is still suitable for the lengthbiased data even without the information of the truncation variable. Meanwhile, large sample properties of the proposed estimators are established, including consistency and asymptotic normality. In addition, the finite sample behavior of the proposed methods and the analysis of three groups of real data are given.