Based on the surveys and the statistic data during 1980-2003, the variation character of grain yield per unit area in Northeast China and its main factors have been discussed by the methods of statistics and grey correlation analysis. The results show that: 1) the grain yield per unit area has been taking on an increasing trend in the recent 20 years. It increased from 2519.80kg/ha in 1980 to 4216.11kg/ha in 2003, with an increasing rate of 67.32%; 2) the variation of grain yield per unit area is considerably prominent and its range is also very great, with the maximal increase rate of 42.59% and maximal decrease rate of 21.13%, respectively, which are far above the whole Chinese average level; 3) the variation of main crops' yield per unit area is remarkable, which takes on the character that the yield of corn is much higher than that of soybean and rice; and 4) the grey correlation analysis shows that the most important factors impacting the variation of grain yield per unit area are the total power of agricultural machinery, the consumption of chemical fertilizer and effective irrigated area. However, the influence of natural disaster and income level should not be ignored. Effective ways to improve grain yield per unit area are to construct farmland improvement groundwork, reclaim the middle- and low-yield farmland, etc.