Interference alignment(IA) has been recognized as a promising technique for obtaining the optimal degrees of freedom(DOF) in interference networks.A closed-form interference alignment design is proposed for three-cell uplink transmissions with heterogeneous DOFs.By exploiting the heterogeneity of DOFs from different transmission links,full or partial interference alignment precoders are calculated at each base station(BS).Aided by information exchange among BSs,the precoders can be finally obtained for all transmission links.Comparing to existing IA methods,the proposed scheme has a closed-form expression.Furthermore,there is no need to go through the iterative adaptation or jointly calculate the precoder and the equalizer.Simulation results show that the proposed design is able to achieve the optimal DOF performance with the advantage of perfect alignment capabilities.