研究了品红(FB)聚合膜修饰玻碳电极的制备及其电化学性质,并用于抗坏血酸(AA)的测定。在 pH7.0的磷酸盐缓冲溶液中,AA 在聚品红修饰玻碳电极上产生一灵敏的氧化峰,峰电流与 AA 的浓度在3.0×10^(-5)～8.7×10^(-3)mol/L 范围内呈良好的线性关系,检出限为 1.0×10^(-5)mol/L。该电极重现性良好,用于维生素 C 片中 AA 的测定,获得满意结果。
A novel capacitive sensor for pazufloxacin mesilate (pazufloxacin) determination was developed by electropolymerizing p-aminobenzene sulfonic (p-ABSA) and molecularly imprinted polymers (MPs), which was synthesized through thermal radical copolymerization of metharylic acid (MAA) and ethylene glycol dimethacrylate (EGDMA) in the presence of pazufloxacin template molecules, on the gold electrode surface. Furthermore, 1-dedecanethiol was used to insulate the modified electrode. Alternating current (ac) impedance experiments were carried out with a Model IM6e to obtain the capacitance responses. Under the optimum conditions, the sensor showed linear capacitance response to pazufloxacin in the range of 5 ng·mL?1 to 5 μg·mL?1 with a relative standard deviation (RSD) 5.3% (n=7) and a detection limit of 1.8 ng·mL?1. The recoveries for different concentration levels of pazufloxacin samples varied from 94.0% to 102.0%. Electrochemical experiments indicated the capacitive sensor exhibited good sensitivity and selectivity and showed excellent parameters of regeneration and stability.
